Shaping the future of relief
The Translational Pain Research Program at the University of Rochester Medical Center in Rochester, NY has conducted over 50 investigator-initiated and multi-center analgesic drug and device clinical trials. The multidisciplinary research team was recognized with a Center of Excellence award in 2013 by the American Pain Society because of its original scientific contributions. In 2019 the National Institutes of Health (NIH) named the Program as one of 12 hubs nationwide for its phase clinical trial network (EPPIC-Net). The program and its team have partnered with over 30 contract research organizations and 70 life science enterprises to develop new treatments for pain.
Research Impact
48
Analgesic Clinical Trials
11
FDA Approved Treatments
170+
Clinical Research Output
- Publications & Presentations -
25,000+
Total Research Participants
Recent Partners in Clinical Research
| Core Translational Pain Research Programs |
Chronic Low Back Pain Syndromes
Our center’s leading study population. A varied set of syndromes that together make up the leading indication for pain treatment worldwide and for which the need for innovation is greatest.
Chronic Neuropathic Pain Syndromes
The lasting painful consequences of nerve injury from neuropathy, shingles, trauma, and surgery are a major target of therapeutic development.
Opioid Alternatives
The need therapies that are as effective as opioids for the acute pain of a bone fracture but with lower risks serious complications continues.
Neuromodulation
Identifying the patients most likely to benefit from neuromodulation, developing standards for clinical trials, and conducting studies to determine the active effects of these therapies
Clinical Trial Design
Collaborating in a nationwide effort to ensure that analgesic clinical trials can distinguish therapies that relieve pain from those that do not
Novel Analgesic Study Endpoints
Developing new ways to examine the pain brought on by specific activities like back pain that is worsened by standing or walking
Antibody Therapy
Evaluating proteins that make nerves less hypersensitive to pain signals in patients with chronic pain
UR-EPPIC-Net Hub
One of 12 Specialized Clinical Centers nationwide leading the study of next generation non-opioid therapies to alleviate pain in a federally-funded network
Innovative Pain Assessment
Finding new ways to recognize and measure the experience of pain.
Resources
To learn more about the scope of our analgesic clinical research and the reach of recent discoveries, please click the links below.
Abstracts/Posters Book Chapters Journal Articles Lay Press
Recent Publications
Tanezumab for chronic low back pain
Published June 2020
